Breakthrough zygomycosis following empirical caspofungin treatment: report of two patients with leukemia and literature review
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چکیده
Breakthrough zygomycosis are increasingly reported life-threatening complications among patients with hematological malignancies, especially since the use of broad spectrum antifungal treatments like voriconazole. We report two cases of breakthrough zygomycosis after caspofungin exposure, with a review of literature.
منابع مشابه
Breakthrough Candida krusei fungemia during fluconazole prophylaxis followed by breakthrough zygomycosis during caspofungin therapy in a patient with severe aplastic anemia who underwent stem cell transplantation.
We report a case of breakthrough invasive zygomycosis in a stem cell transplant recipient who was receiving caspofungin for treatment of a breakthrough Candida krusei fungemia that occurred during fluconazole prophylaxis. Also, patients receiving the echinocandin caspofungin remain at risk for pathogens, such as zygomycetes, that are intrinsically resistant to this agent.
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تاریخ انتشار 2010